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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2321078
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Relb
Name: RELB proto-oncogene, NF-kB subunit
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Relbincreases expressionISORELB (Homo sapiens)6480464CTDOzone results in increased expression of RELB mRNAPMID:23033980 PMID:31476115
Relbmultiple interactionsISORELB (Homo sapiens)6480464CTD[Aripiprazole co-treated with Ozone] results in increased expression of RELB mRNA; [Oxygen co-treated with Ozone co-treated with Cannabidiol] results in decreased expression of RELB mRNA; [Oxygen co-treated with Ozone] inhibits the reaction [Cannabidiol results in increased expression of RELB mRNA]; [Oxygen co-treated with Ozone] results in decreased expression of RELB mRNAPMID:31476115 PMID:32992648
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