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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1623040
Species: Mus musculus
RGD Object: Gene
Symbol: Cenpf
Name: centromere protein F
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cenpfdecreases expressionEXP 6480464CTDOzone results in decreased expression of CENPF mRNAPMID:24336422
Cenpfmultiple interactionsEXP 6480464CTD[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of CENPF mRNA; [Air Pollutants results in increased abundance of Ozone] which results in increased expression of CENPF mRNA; [NOTCH3 gene mutant form affects the susceptibility to Ozone] which affects the expression of CENPF mRNAPMID:25658374 PMID:27106289 PMID:34911549
Cenpfmultiple interactionsISOCENPF (Homo sapiens)6480464CTD[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of CENPF mRNA; [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of CENPF mRNA; [Volatile Organic Compounds co-treated with Ozone] results in increased oxidation of CENPF mRNAPMID:32699268
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