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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1589741
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rgs16
Name: regulator of G-protein signaling 16
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rgs16increases expressionEXP 6480464CTDOzone results in increased expression of RGS16 mRNAPMID:28623178
Rgs16increases expressionISORgs16 (Mus musculus)6480464CTDOzone results in increased expression of RGS16 mRNAPMID:25658374 PMID:33026818
Rgs16multiple interactionsISORgs16 (Mus musculus)6480464CTD[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of RGS16 mRNA; [Air Pollutants results in increased abundance of Ozone] which results in increased expression of RGS16 mRNA; [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of RGS16 mRNAPMID:25658374 PMID:27106289 PMID:34911549
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