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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1552166
Species: Mus musculus
RGD Object: Gene
Symbol: Il23a
Name: interleukin 23, alpha subunit p19
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il23amultiple interactionsEXP 6480464CTD[Air Pollutants results in increased abundance of Ozone] which results in increased expression of IL23A mRNA; [TNFRSF1B co-treated with CPE] promotes the reaction [[Air Pollutants results in increased abundance of Ozone] which results in increased expression of IL23A mRNA]; IL23A promotes the reaction [[Air Pollutants results in increased abundance of Ozone] which results in increased expression of IL17A protein]PMID:24823369 PMID:27043160
Il23aincreases expressionISOIL23A (Homo sapiens)6480464CTDOzone results in increased expression of IL23A mRNAPMID:31476115
Il23amultiple interactionsISOIL23A (Homo sapiens)6480464CTD[Aripiprazole co-treated with Ozone] results in increased expression of IL23A mRNAPMID:31476115
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