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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311060
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ctps1
Name: CTP synthase 1
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ctps1increases expressionISOCtps1 (Mus musculus)6480464CTDOzone results in increased expression of CTPS1 mRNAPMID:25658374
Ctps1multiple interactionsISOCTPS1 (Homo sapiens)6480464CTD[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of CTPS1 mRNA; [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of and results in increased oxidation of CTPS1 mRNA; [Volatile Organic Compounds co-treated with Ozone] results in decreased expression of and results in increased oxidation of CTPS1 mRNAPMID:32699268
Ctps1multiple interactionsISOCtps1 (Mus musculus)6480464CTD[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of CTPS1 mRNA; [Air Pollutants results in increased abundance of Ozone] which results in increased expression of CTPS1 mRNA; TTPA protein affects the reaction [Ozone results in increased expression of CTPS1 mRNA]PMID:19555225 PMID:34911549
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