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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308252
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ffar4
Name: free fatty acid receptor 4
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ffar4increases expressionEXP 6480464CTDOzone results in increased expression of FFAR4 mRNAPMID:29329427
Ffar4multiple interactionsEXP 6480464CTDFish Oils inhibits the reaction [Ozone results in increased expression of FFAR4 mRNA]PMID:29329427
Ffar4multiple interactionsISOFfar4 (Mus musculus)6480464CTD[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of FFAR4 mRNA; [Air Pollutants results in increased abundance of Ozone] which results in increased expression of FFAR4 mRNAPMID:34911549
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