GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cftr | multiple interactions | EXP | | 6480464 | CTD | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of CFTR mRNA | PMID:34911549 | Cftr | decreases expression | ISO | CFTR (Homo sapiens) | 6480464 | CTD | Ozone results in decreased expression of CFTR mRNA; Ozone results in decreased expression of CFTR protein | PMID:19061877 | Cftr | increases expression | ISO | CFTR (Homo sapiens) | 6480464 | CTD | Ozone results in increased expression of CFTR mRNA | PMID:27206323 | Cftr | multiple interactions | ISO | CFTR (Homo sapiens) | 6480464 | CTD | Acetylcysteine inhibits the reaction [Ozone results in decreased expression of CFTR mRNA]; Acetylcysteine inhibits the reaction [Ozone results in decreased expression of CFTR protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Ozone results in decreased expression of CFTR mRNA]; Ozone inhibits the reaction [Colforsin results in increased activity of CFTR protein]; pimagedine inhibits the reaction [Ozone results in decreased expression of CFTR mRNA]; pimagedine inhibits the reaction [Ozone results in decreased expression of CFTR protein] | PMID:19061877 | |
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