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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11484
Species: Mus musculus
RGD Object: Gene
Symbol: Vdr
Name: vitamin D (1,25-dihydroxyvitamin D3) receptor
Acc ID: CHEBI:2567
Term: alendronic acid
Definition: A 1,1-bis(phosphonic acid) that is methanebis(phosphonic acid) in which the two methylene hydrogens are replaced by hydroxy and 3-aminopropyl groups.
Chemical ID: MESH:D019386
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vdraffects response to substanceISOVDR (Homo sapiens)6480464CTDVDR gene polymorphism affects the susceptibility to AlendronatePMID:12608943 PMID:15739035
Vdrmultiple interactionsISOVDR (Homo sapiens)6480464CTDVDR gene polymorphism affects the susceptibility to [Alendronate co-treated with Estrogens, Conjugated (USP) co-treated with Medroxyprogesterone Acetate]; VDR gene polymorphism affects the susceptibility to [Alendronate co-treated with Raloxifene Hydrochloride]PMID:15739035
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