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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620021
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ihh
Name: Indian hedgehog signaling molecule
Acc ID: CHEBI:2564
Term: aldrin
Definition: An organochlorine compound resulting from the Diels-Alder reaction of hexachlorocyclopentadiene with norbornadiene. A proinsecticide (by epoxidation of the non-chlorinated double bond to give dieldrin), it was widely used as an insecticide before being banned in the 1970s as a persistent organic pollutant.
Chemical ID: MESH:D000452
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:15522376480464CTDAldrin results in increased expression of IHH mRNA

PMID:18579281
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.