GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sp1 | increases expression | ISO | Sp1 (Rattus norvegicus) | 6480464 | CTD | 9,10-Dimethyl-1,2-benzanthracene results in increased expression of SP1 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of SP1 protein | PMID:36863560 | Sp1 | increases expression | ISO | SP1 (Homo sapiens) | 6480464 | CTD | 9,10-Dimethyl-1,2-benzanthracene results in increased expression of SP1 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of SP1 protein | PMID:29663660 | Sp1 | multiple interactions | ISO | SP1 (Homo sapiens) | 6480464 | CTD | [[9,10-Dimethyl-1,2-benzanthracene co-treated with 12-O-tetradecanoylphorbol-1,3-acetate] results in increased activity of TRP53 protein] inhibits the reaction [SP1 protein binds to SOD2 promoter]; [[[9,10-Dimethyl-1,2-benzanthracene co-treated with 12-O-tetradecanoylphorbol-1,3-acetate] results in increased activity of TRP53 protein] inhibits the reaction [SP1 protein binds to SOD2 promoter]] which results in decreased expression of SOD2 mRNA; SP1 protein affects the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CTNNB1 protein] | PMID:22009531 PMID:29663660 | | ||||||||||||||||||||||
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