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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1558362
Species: Mus musculus
RGD Object: Gene
Symbol: Aph1b
Name: aph1 homolog B, gamma secretase subunit
Acc ID: CHEBI:25434
Term: bis(2-chloroethyl) sulfide
Definition: An ethyl sulfide that is diethyl sulfide in which a hydrogen from each of the terminal methyl groups is replaced by a chlorine. It is a powerful vesicant regulated under the Chemical Weapons Convention.
Chemical ID: MESH:D009151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Aph1bincreases expressionISOAPH1B (Homo sapiens)6480464CTDMustard Gas results in increased expression of APH1B mRNAPMID:25102026
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