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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1316728
Species: Mus musculus
RGD Object: Gene
Symbol: Rad51
Name: RAD51 recombinase
Acc ID: CHEBI:25434
Term: bis(2-chloroethyl) sulfide
Definition: An ethyl sulfide that is diethyl sulfide in which a hydrogen from each of the terminal methyl groups is replaced by a chlorine. It is a powerful vesicant regulated under the Chemical Weapons Convention.
Chemical ID: MESH:D009151
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rad51decreases expressionEXP 6480464CTDMustard Gas results in decreased expression of RAD51 mRNAPMID:19778212
Rad51affects localizationISORAD51 (Homo sapiens)6480464CTDMustard Gas affects the localization of RAD51 proteinPMID:20435105
Rad51decreases expressionISORAD51 (Homo sapiens)6480464CTDMustard Gas results in decreased expression of RAD51 mRNAPMID:33491125
Rad51decreases response to substanceISORAD51 (Homo sapiens)6480464CTDRAD51 protein results in decreased susceptibility to Mustard GasPMID:20435105
Rad51multiple interactionsISORAD51 (Homo sapiens)6480464CTDBRCA2 protein inhibits the reaction [Mustard Gas affects the localization of RAD51 protein]PMID:20435105
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