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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3920
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnfrsf4
Name: TNF receptor superfamily member 4
Acc ID: CHEBI:25351
Term: mevalonic acid
Definition: A racemate composed of equimolar amounts of (R)- and (S)-mevalonic acid.
Chemical ID: MESH:D008798
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfrsf4multiple interactionsISOTNFRSF4 (Homo sapiens)6480464CTDMevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of TNFRSF4 mRNA]]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [IFNG results in increased expression of TNFRSF4 protein]]PMID:19589242
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