GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ifng | affects expression | EXP | | 6480464 | CTD | Mercury affects the expression of IFNG mRNA; Mercury affects the expression of IFNG protein | PMID:12928768 PMID:15910788 | Ifng | decreases secretion | EXP | | 6480464 | CTD | Mercury results in decreased secretion of IFNG protein | PMID:15910788 | Ifng | increases expression | EXP | | 6480464 | CTD | Mercury results in increased expression of IFNG mRNA | PMID:25237059 | Ifng | multiple interactions | EXP | | 6480464 | CTD | [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IFNG protein; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of FCGR1 mRNA]; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IL4 mRNA]; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF1 mRNA]; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IRF8 mRNA]; IFNG gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of TNF mRNA]; IL6 gene mutant form inhibits the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of IFNG mRNA]; N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline inhibits the reaction [Mercury results in increased expression of IFNG mRNA] | PMID:25237059 PMID:28453771 | Ifng | increases expression | ISO | IFNG (Homo sapiens) | 6480464 | CTD | Mercury results in increased expression of IFNG protein | PMID:20176347 | | ||||||||||||||||||||||
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