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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621252
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mt3
Name: metallothionein 3
Acc ID: CHEBI:25195
Term: mercury atom
Definition: A zinc group element atom that has formula Hg.
Chemical ID: MESH:D008628
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mt3increases expressionEXP 6480464CTDMercury results in increased expression of MT3 mRNAPMID:9587011
Mt3affects bindingISOMt3 (Mus musculus)6480464CTDMercury binds to MT3 proteinPMID:15782327
Mt3affects response to substanceISOMt3 (Mus musculus)6480464CTDMT3 protein affects the susceptibility to MercuryPMID:30103553
Mt3increases expressionISOMt3 (Mus musculus)6480464CTDMercury results in increased expression of MT3 mRNA; Mercury results in increased expression of MT3 proteinPMID:15138662 PMID:17018868 PMID:8917669
Mt3multiple interactionsISOMt3 (Mus musculus)6480464CTD[MT3 protein affects the susceptibility to Mercury] which affects the expression of CCL7 mRNA; [MT3 protein affects the susceptibility to Mercury] which affects the expression of MT2 mRNA; MT3 protein affects the reaction [Mercury results in increased expression of CCL3 mRNA]PMID:30103553
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