GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Gclc | multiple interactions | EXP | | 6480464 | CTD | [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of GCLC mRNA; [Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of GCLC protein; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of GCLC mRNA]; Curcumin promotes the reaction [[Mercuric Chloride results in increased abundance of Mercury] which results in increased expression of GCLC protein] | PMID:27837179 | Gclc | affects response to substance | ISO | GCLC (Homo sapiens) | 6480464 | CTD | GCLC gene SNP affects the susceptibility to Mercury | PMID:22236634 | Gclc | increases expression | ISO | GCLC (Homo sapiens) | 6480464 | CTD | Mercury results in increased expression of GCLC mRNA | PMID:17547211 | Gclc | multiple interactions | ISO | GCLC (Homo sapiens) | 6480464 | CTD | [Mercuric Chloride results in increased abundance of Mercury] which results in decreased expression of GCLC protein; GCLC gene polymorphism promotes the reaction [GSTP1 gene polymorphism affects the abundance of Mercury] | PMID:19515364 PMID:30359721 | | ||||||||||||||||||||||
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