GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | MT2A | affects abundance | EXP | | 6480464 | CTD | MT2A gene SNP affects the abundance of Mercury | PMID:22233731 | MT2A | affects response to substance | EXP | | 6480464 | CTD | MT2A gene polymorphism affects the susceptibility to Mercury | PMID:23827881 | MT2A | multiple interactions | EXP | | 6480464 | CTD | [MT1M gene polymorphism co-treated with MT2A gene polymorphism] affects the susceptibility to Mercury | PMID:23827881 | MT2A | affects binding | ISO | Mt2 (Mus musculus) | 6480464 | CTD | Mercury binds to MT2 protein | PMID:15603537 | MT2A | increases expression | ISO | Mt2A (Rattus norvegicus) | 6480464 | CTD | Mercury results in increased expression of MT2A mRNA | PMID:2771874 PMID:9462895 PMID:9587011 | MT2A | increases expression | ISO | Mt2 (Mus musculus) | 6480464 | CTD | Mercury results in increased expression of MT2 mRNA; Mercury results in increased expression of MT2 protein | PMID:15138662 PMID:17018868 PMID:21628964 PMID:8917669 | MT2A | increases response to substance | ISO | Mt2 (Mus musculus) | 6480464 | CTD | MT2 gene mutant form results in increased susceptibility to Mercury | PMID:15782327 | MT2A | multiple interactions | ISO | Mt2 (Mus musculus) | 6480464 | CTD | [MT1 co-treated with MT2] affects the susceptibility to Mercury; [MT3 protein affects the susceptibility to Mercury] which affects the expression of MT2 mRNA | PMID:22008530 PMID:30103553 | | ||||||||||||||||||||||
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