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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10742
Species: Mus musculus
RGD Object: Gene
Symbol: Hspa5
Name: heat shock protein 5
Acc ID: CHEBI:25195
Term: mercury atom
Definition: A zinc group element atom that has formula Hg.
Chemical ID: MESH:D008628
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hspa5affects expressionISOHspa5 (Rattus norvegicus)6480464CTDMercury affects the expression of HSPA5 mRNAPMID:15111246
Hspa5multiple interactionsISOHspa5 (Rattus norvegicus)6480464CTDMercury promotes the reaction [HSPA5 protein binds to FOS enhancer]; Mercury promotes the reaction [HSPA5 protein binds to HRAS enhancer]; Mercury results in increased expression of and results in increased activity of HSPA5 proteinPMID:15111246
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