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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1557448
Species: Mus musculus
RGD Object: Gene
Symbol: Top2b
Name: topoisomerase (DNA) II beta
Acc ID: CHEBI:25187
Term: p-menthan-3-ol
Definition: Any secondary alcohol that is one of the eight possible diastereoisomers of 5-methyl-2-(propan-2-yl)cyclohexan-1-ol.
Chemical ID: MESH:D008610
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Top2bdecreases activityISORGD:13506376480464CTDMenthol results in decreased activity of TOP2B protein

PMID:16158947
Top2bincreases expressionISORGD:13506376480464CTDMenthol results in increased expression of TOP2B mRNA

PMID:26760959
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