GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tyr | multiple interactions | ISO | Tyr (Mus musculus) | 6480464 | CTD | [Fenofibrate results in decreased chemical synthesis of Melanins] which results in decreased expression of TYR | PMID:23872139 | Tyr | multiple interactions | ISO | TYR (Homo sapiens) | 6480464 | CTD | [CLDN3 protein results in increased abundance of Copper] promotes the reaction [[TYR protein results in increased oxidation of Levodopa] which results in increased chemical synthesis of Melanins]; [CLDN4 protein results in increased abundance of Copper] promotes the reaction [[TYR protein results in increased oxidation of Levodopa] which results in increased chemical synthesis of Melanins]; [Tetrachlorodibenzodioxin results in increased activity of TYR protein] which results in increased abundance of Melanins; [TYR protein co-treated with ATP7A protein] results in increased abundance of Melanins; [TYR protein results in decreased expression of and results in decreased activity of PLD1 protein] which results in decreased abundance of Melanins; [TYR protein results in increased oxidation of Levodopa] which results in increased chemical synthesis of Melanins | PMID:11092760 PMID:14615486 PMID:20973933 PMID:23053666 | | ||||||||||||||||||||||
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