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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619934
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2c6
Name: cytochrome P450, family 2, subfamily C, polypeptide 6
Acc ID: CHEBI:251412
Term: adinazolam
Definition: A triazolo[4,3-a][1,4]benzodiazepine having a dimethylaminomethyl group at the 1-position, a phenyl group at the 6-position and a chloro substituent at the 8-position.
Chemical ID: MESH:C039668
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2c6decreases methylationISOCYP2C19 (Homo sapiens)6480464CTDCYP2C19 protein results in decreased methylation of adinazolamPMID:9600717
Cyp2c6multiple interactionsISOCYP2C19 (Homo sapiens)6480464CTDOmeprazole inhibits the reaction [CYP2C19 protein results in decreased methylation of adinazolam]PMID:9600717
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