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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731267
Species: Homo sapiens
RGD Object: Gene
Symbol: PKIA
Name: cAMP-dependent protein kinase inhibitor alpha
Acc ID: CHEBI:2504
Term: aflatoxin B1
Definition: An aflatoxin having a tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene skeleton with oxygen functionality at positions 1, 4 and 11.
Chemical ID: MESH:D016604
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:7312686480464CTDAflatoxin B1 results in decreased expression of PKIA mRNA

PMID:19770486
increases expressionISORGD:6210216480464CTDAflatoxin B1 results in increased expression of PKIA mRNA

PMID:23630614, PMID:25378103
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