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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68557
Species: Mus musculus
RGD Object: Gene
Symbol: Ccnd1
Name: cyclin D1
Acc ID: CHEBI:2504
Term: aflatoxin B1
Definition: An aflatoxin having a tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene skeleton with oxygen functionality at positions 1, 4 and 11.
Chemical ID: MESH:D016604
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccnd1decreases expressionEXP 6480464CTDAflatoxin B1 results in decreased expression of CCND1 mRNA; Aflatoxin B1 results in decreased expression of CCND1 proteinPMID:29274131
Ccnd1affects expressionISOCCND1 (Homo sapiens)6480464CTDAflatoxin B1 affects the expression of CCND1 proteinPMID:20106945
Ccnd1decreases expressionISOCCND1 (Homo sapiens)6480464CTDAflatoxin B1 results in decreased expression of CCND1 proteinPMID:34396909
Ccnd1increases expressionISOCcnd1 (Rattus norvegicus)6480464CTDAflatoxin B1 results in increased expression of CCND1 mRNAPMID:14600272 PMID:15890375 PMID:23385219 PMID:23630614 PMID:34015426
Ccnd1increases expressionISOCCND1 (Homo sapiens)6480464CTDAflatoxin B1 results in increased expression of CCND1 mRNAPMID:22100608
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