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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631419
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ric8b
Name: RIC8 guanine nucleotide exchange factor B
Acc ID: CHEBI:2504
Term: aflatoxin B1
Definition: An aflatoxin having a tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene skeleton with oxygen functionality at positions 1, 4 and 11.
Chemical ID: MESH:D016604
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases methylationISORGD:16056576480464CTDAflatoxin B1 results in decreased methylation of RIC8B gene

PMID:27153756
increases expressionISORGD:15584266480464CTDAflatoxin B1 results in increased expression of RIC8B mRNA

PMID:19770486
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