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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620454
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Plpp3
Name: phospholipid phosphatase 3
Acc ID: CHEBI:2504
Term: aflatoxin B1
Definition: An aflatoxin having a tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene skeleton with oxygen functionality at positions 1, 4 and 11.
Chemical ID: MESH:D016604
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Plpp3decreases methylationISOPLPP3 (Homo sapiens)6480464CTDAflatoxin B1 results in decreased methylation of PLPP3 genePMID:27153756
Plpp3increases expressionISOPlpp3 (Mus musculus)6480464CTDAflatoxin B1 results in increased expression of PLPP3 mRNAPMID:19770486
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