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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1350006
Species: Homo sapiens
RGD Object: Gene
Symbol: UGT2B17
Name: UDP glucuronosyltransferase family 2 member B17
Acc ID: CHEBI:2504
Term: aflatoxin B1
Definition: An aflatoxin having a tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene skeleton with oxygen functionality at positions 1, 4 and 11.
Chemical ID: MESH:D016604
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
UGT2B17decreases methylationEXP 6480464CTDAflatoxin B1 results in decreased methylation of UGT2B17 genePMID:27153756
UGT2B17increases expressionEXP 6480464CTDAflatoxin B1 results in increased expression of UGT2B17 mRNAPMID:21641981
UGT2B17increases expressionISOUgt2b1 (Rattus norvegicus)6480464CTDAflatoxin B1 results in increased expression of UGT2B17 mRNAPMID:23052194 PMID:33354967
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