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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1312165
Species: Mus musculus
RGD Object: Gene
Symbol: Rabgap1l
Name: RAB GTPase activating protein 1-like
Acc ID: CHEBI:2504
Term: aflatoxin B1
Definition: An aflatoxin having a tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene skeleton with oxygen functionality at positions 1, 4 and 11.
Chemical ID: MESH:D016604
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rabgap1ldecreases expressionEXP 6480464CTDAflatoxin B1 results in decreased expression of RABGAP1L mRNAPMID:19770486
Rabgap1laffects expressionISORABGAP1L (Homo sapiens)6480464CTDAflatoxin B1 affects the expression of RABGAP1L proteinPMID:20106945
Rabgap1laffects methylationISORABGAP1L (Homo sapiens)6480464CTDAflatoxin B1 affects the methylation of RABGAP1L intronPMID:30157460
Rabgap1ldecreases expressionISORABGAP1L (Homo sapiens)6480464CTDAflatoxin B1 results in decreased expression of RABGAP1L mRNAPMID:21632981 PMID:21641981 PMID:22100608 PMID:27153756 PMID:30157460
Rabgap1lincreases methylationISORABGAP1L (Homo sapiens)6480464CTDAflatoxin B1 results in increased methylation of RABGAP1L gene; Aflatoxin B1 results in increased methylation of RABGAP1L promoterPMID:27153756 PMID:30157460
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