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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1309416
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fars2
Name: phenylalanyl-tRNA synthetase 2, mitochondrial
Acc ID: CHEBI:2504
Term: aflatoxin B1
Definition: An aflatoxin having a tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene skeleton with oxygen functionality at positions 1, 4 and 11.
Chemical ID: MESH:D016604
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fars2affects expressionISOFARS2 (Homo sapiens)6480464CTDAflatoxin B1 affects the expression of FARS2 proteinPMID:20106945
Fars2affects methylationISOFARS2 (Homo sapiens)6480464CTDAflatoxin B1 affects the methylation of FARS2 intronPMID:30157460
Fars2decreases expressionISOFARS2 (Homo sapiens)6480464CTDAflatoxin B1 results in decreased expression of FARS2 mRNAPMID:21641981 PMID:27153756
Fars2decreases expressionISOFars2 (Mus musculus)6480464CTDAflatoxin B1 results in decreased expression of FARS2 mRNAPMID:19770486
Fars2increases methylationISOFARS2 (Homo sapiens)6480464CTDAflatoxin B1 results in increased methylation of FARS2 genePMID:27153756
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