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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11329
Species: Mus musculus
RGD Object: Gene
Symbol: Sod1
Name: superoxide dismutase 1, soluble
Acc ID: CHEBI:2504
Term: aflatoxin B1
Definition: An aflatoxin having a tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene skeleton with oxygen functionality at positions 1, 4 and 11.
Chemical ID: MESH:D016604
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sod1decreases expressionEXP 6480464CTDAflatoxin B1 results in decreased expression of SOD1 mRNAPMID:35063475
Sod1increases expressionEXP 6480464CTDAflatoxin B1 results in increased expression of SOD1 mRNAPMID:19770486
Sod1multiple interactionsEXP 6480464CTDCurcumin inhibits the reaction [Aflatoxin B1 results in decreased expression of SOD1 mRNA]PMID:35063475
Sod1decreases expressionISOSod1 (Rattus norvegicus)6480464CTDAflatoxin B1 results in decreased expression of SOD1 mRNAPMID:28442411
Sod1increases expressionISOSOD1 (Homo sapiens)6480464CTDAflatoxin B1 results in increased expression of SOD1 mRNAPMID:27017951
Sod1multiple interactionsISOSOD1 (Homo sapiens)6480464CTD[gluconic acid co-treated with Zinc Sulfate] promotes the reaction [Aflatoxin B1 results in increased expression of SOD1 mRNA]; Zinc Sulfate promotes the reaction [Aflatoxin B1 results in increased expression of SOD1 mRNA]PMID:27017951
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