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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731751
Species: Homo sapiens
RGD Object: Gene
Symbol: SLC5A5
Name: solute carrier family 5 member 5
Acc ID: CHEBI:24858
Term: iodide salt
Definition: null
Chemical ID: MESH:D007454
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SLC5A5increases uptakeEXP 6480464CTDSLC5A5 protein results in increased uptake of IodidesPMID:15671536 PMID:15850642 PMID:15941870 PMID:16234306
SLC5A5multiple interactionsEXP 6480464CTDDexamethasone promotes the reaction [SLC5A5 protein results in increased uptake of Iodides]; perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodides]; potassium perchlorate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodides]; thiocyanate inhibits the reaction [SLC5A5 protein results in increased uptake of Iodides]PMID:15671536 PMID:15850642 PMID:15941870 PMID:16234306
SLC5A5affects expressionISOSlc5a5 (Rattus norvegicus)6480464CTDIodides deficiency affects the expression of SLC5A5 mRNAPMID:21623536
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