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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732740
Species: Homo sapiens
RGD Object: Gene
Symbol: CAT
Name: catalase
Acc ID: CHEBI:24814
Term: indole-3-methanol
Definition: An indolyl alcohol carrying a hydroxymethyl group at position 3. It is a constituent of the cruciferous vegetables and had anticancer activity.
Chemical ID: MESH:C016517
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CATincreases activityISOCat (Mus musculus)6480464CTDindole-3-carbinol results in increased activity of CAT proteinPMID:29775573
CATmultiple interactionsISOCat (Rattus norvegicus)6480464CTDindole-3-carbinol inhibits the reaction [Thioacetamide results in decreased expression of CAT protein]PMID:37150287
CATmultiple interactionsISOCat (Mus musculus)6480464CTDindole-3-carbinol inhibits the reaction [Doxorubicin results in decreased activity of CAT protein]PMID:29775573
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