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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619842
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pex11a
Name: peroxisomal biogenesis factor 11 alpha
Acc ID: CHEBI:24814
Term: indole-3-methanol
Definition: An indolyl alcohol carrying a hydroxymethyl group at position 3. It is a constituent of the cruciferous vegetables and had anticancer activity.
Chemical ID: MESH:C016517
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PEX11A mRNA, [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of PEX11A mRNA, Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of PEX11A mRNA]

PMID:22129741
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.