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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730901
Species: Homo sapiens
RGD Object: Gene
Symbol: HMOX1
Name: heme oxygenase 1
Acc ID: CHEBI:24757
Term: hypochlorous acid
Definition: A chlorine oxoacid with formula HOCl; a weak, unstable acid, it is the active form of chlorine in water.
Chemical ID: MESH:D006997
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HMOX1increases expressionEXP 6480464CTDHypochlorous Acid results in increased expression of HMOX1 mRNAPMID:18156441
HMOX1multiple interactionsEXP 6480464CTDAcetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of HMOX1 mRNA]PMID:18156441
HMOX1increases expressionISOHmox1 (Mus musculus)6480464CTDHypochlorous Acid results in increased expression of HMOX1 mRNA; Hypochlorous Acid results in increased expression of HMOX1 proteinPMID:17980396 PMID:19376150
HMOX1multiple interactionsISOHmox1 (Mus musculus)6480464CTD[Quercetin co-treated with Hypochlorous Acid] results in increased expression of HMOX1 proteinPMID:24017971
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