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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730935
Species: Homo sapiens
RGD Object: Gene
Symbol: HIF1A
Name: hypoxia inducible factor 1 subunit alpha
Acc ID: CHEBI:24631
Term: hydrazines
Definition: Hydrazine (diazane) and its substituted derivatives.
Chemical ID: MESH:D006834
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HIF1Amultiple interactionsISOHif1a (Rattus norvegicus)6480464CTD[cobaltous chloride results in increased activity of HIF1A protein] which results in decreased susceptibility to Hydrazines; Cadmium Chloride inhibits the reaction [[cobaltous chloride results in increased activity of HIF1A protein] which results in decreased susceptibility to Hydrazines]PMID:14980978
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