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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1558154
Species: Mus musculus
RGD Object: Gene
Symbol: Appl2
Name: adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
Acc ID: CHEBI:24556
Term: 1,3,5-trinitro-1,3,5-triazinane
Definition: An N-nitro compound that is 1,3,5-triazinane in which all three of the hydrogens attached to the nitrogens have been replaced by nitro groups. It is widely used in both industrial and military explosives.
Chemical ID: MESH:C009160
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Appl2decreases expressionISOAppl2 (Rattus norvegicus)6480464CTDcyclonite results in decreased expression of APPL2 mRNAPMID:25559034
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