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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620099
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc17a1
Name: solute carrier family 17 member 1
Acc ID: CHEBI:2453
Term: acyclovir
Definition: An oxopurine that is guanine substituted by a (2-hydroxyethoxy)methyl substituent at position 9. Used in the treatment of viral infections.
Chemical ID: MESH:D000212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDAcyclovir results in decreased expression of SLC17A1 mRNA, Acyclovir results in decreased expression of SLC17A1 protein

PMID:14675048
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.