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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732555
Species: Homo sapiens
RGD Object: Gene
Symbol: GJB1
Name: gap junction protein beta 1
Acc ID: CHEBI:23995
Term: N-ethyl-N-nitrosourea
Definition: A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by ethyl and nitroso groups.
Chemical ID: MESH:D005038
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GJB1multiple interactionsISOGjb1 (Rattus norvegicus)6480464CTD[Ethylnitrosourea co-treated with chlorendic acid] results in decreased expression of GJB1 protein; [Ethylnitrosourea co-treated with ciprofibrate] results in decreased expression of GJB1 protein; [Ethylnitrosourea co-treated with Dioxins] results in decreased expression of GJB1 protein; [Ethylnitrosourea co-treated with Phenobarbital] results in decreased expression of GJB1 protein; [Ethylnitrosourea co-treated with pirinixic acid] results in decreased expression of GJB1 protein; [Ethylnitrosourea co-treated with Tamoxifen] results in decreased expression of GJB1 proteinPMID:1973356
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