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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621063
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Csf1
Name: colony stimulating factor 1
Acc ID: CHEBI:23924
Term: enzyme inhibitor
Definition: A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
Chemical ID: MESH:D004791
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Csf1decreases response to substanceISOCSF1 (Homo sapiens)6480464CTDEnzyme Inhibitors results in decreased susceptibility to CSF1 proteinPMID:8193360
Csf1multiple interactionsISOCSF1 (Homo sapiens)6480464CTDEnzyme Inhibitors inhibits the reaction [CSF1 protein promotes the reaction [Lipopolysaccharides results in increased chemical synthesis of Nitric Oxide]]; Enzyme Inhibitors inhibits the reaction [Lipopolysaccharides results in decreased susceptibility to CSF1 protein]; Enzyme Inhibitors inhibits the reaction [Nitric Oxide results in decreased activity of CSF1 protein]PMID:8193360
Csf1multiple interactionsISOCsf1 (Mus musculus)6480464CTDEnzyme Inhibitors inhibits the reaction [Lipopolysaccharides results in decreased susceptibility to CSF1 protein]PMID:8193360
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