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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1354508
Species: Homo sapiens
RGD Object: Gene
Symbol: CSF2
Name: colony stimulating factor 2
Acc ID: CHEBI:23924
Term: enzyme inhibitor
Definition: A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
Chemical ID: MESH:D004791
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CSF2decreases response to substanceISOCsf2 (Mus musculus)6480464CTDEnzyme Inhibitors results in decreased susceptibility to CSF2 proteinPMID:8193360
CSF2multiple interactionsISOCsf2 (Mus musculus)6480464CTD[Benzene co-treated with Enzyme Inhibitors] promotes the reaction [[Lipopolysaccharides co-treated with CSF2 protein] results in increased chemical synthesis of Nitric Oxide]; Enzyme Inhibitors results in increased susceptibility to [Lipopolysaccharides co-treated with CSF2 protein]PMID:8193360
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