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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10510
Species: Mus musculus
RGD Object: Gene
Symbol: Egf
Name: epidermal growth factor
Acc ID: CHEBI:23924
Term: enzyme inhibitor
Definition: A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
Chemical ID: MESH:D004791
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDEnzyme Inhibitors inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein], Enzyme Inhibitors inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]

PMID:25825487
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.