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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732308
Species: Homo sapiens
RGD Object: Gene
Symbol: NOX1
Name: NADPH oxidase 1
Acc ID: CHEBI:23899
Term: icosanoid
Definition: Any member of the group of signalling molecules arising from oxidation of the three C20 essential fatty acids (EFAs) icosapentaenoic acid (EPA), arachidonic acid (AA) and dihomo-gamma-linolenic acid (DGLA).
Chemical ID: MESH:D015777
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NOX1multiple interactionsISONox1 (Rattus norvegicus)6480464CTDEicosanoids analog inhibits the reaction [Cisplatin results in increased expression of NOX1 mRNA]PMID:23603837
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