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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62221
Species: Mus musculus
RGD Object: Gene
Symbol: Hif1a
Name: hypoxia inducible factor 1, alpha subunit
Acc ID: CHEBI:23765
Term: quinolone
Definition: null
Chemical ID: MESH:D015363
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hif1amultiple interactionsISOHIF1A (Homo sapiens)6480464CTDQuinolones inhibits the reaction [Mustard Gas inhibits the reaction [Oxygen deficiency results in increased stability of HIF1A protein]]; Quinolones promotes the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; Quinolones results in increased expression of and affects the localization of HIF1A proteinPMID:26082309
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