Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	1345118
Species:	Homo sapiens
RGD Object:	Gene
Symbol:	PARP1
Name:	poly(ADP-ribose) polymerase 1

Acc ID:	CHEBI:23704
Term:	diepoxybutane
Definition:	An epoxide that has formula C4H6O2.
Chemical ID:	MESH:C007366

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
PARP1	increases cleavage	EXP		6480464	CTD	diepoxybutane results in increased cleavage of PARP1 protein	PMID:14998682

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.