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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70500
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk1
Name: mitogen activated protein kinase 1
Acc ID: CHEBI:23527
Term: cytochalasin B
Definition: An organic heterotricyclic compound, that is a mycotoxin which is cell permeable an an inhibitor of cytoplasmic division by blocking the formation of contractile microfilaments.
Chemical ID: MESH:D003571
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk1multiple interactionsISORGD:7325026480464CTD[Cytochalasin B co-treated with C5 protein] results in increased phosphorylation of and results in increased activity of MAPK1 protein resveratrol analog inhibits the reaction [[Cytochalasin B co-treated with C5 protein] results in increased phosphorylation of and results in increased activity of MAPK1 protein]

PMID:18776917
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