Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731729
Species: Mus musculus
RGD Object: Gene
Symbol: Casp1
Name: caspase 1
Acc ID: CHEBI:23414
Term: copper(II) sulfate
Definition: A metal sulfate compound having copper(2+) as the metal ion.
Chemical ID: MESH:D019327
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp1increases cleavageEXP 6480464CTDCopper Sulfate results in increased cleavage of CASP1 mRNAPMID:37353053
Casp1increases expressionEXP 6480464CTDCopper Sulfate results in increased expression of CASP1 mRNAPMID:37353053
Casp1multiple interactionsEXP 6480464CTDroflupram inhibits the reaction [Copper Sulfate results in increased cleavage of CASP1 mRNA]; roflupram inhibits the reaction [Copper Sulfate results in increased expression of CASP1 mRNA]PMID:37353053
Casp1decreases expressionISOCASP1 (Homo sapiens)6480464CTDCopper Sulfate results in decreased expression of CASP1 mRNAPMID:19549813
Go Back to source page   Continue to Ontology report