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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1317785
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp2c65
Name: cytochrome P450, family 2, subfamily c, polypeptide 65
Acc ID: CHEBI:23403
Term: coumarins
Definition: null
Chemical ID: MESH:D003374
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2c65increases metabolic processingISOCYP2C9 (Homo sapiens)6480464CTDCYP2C9 protein results in increased metabolism of CoumarinsPMID:14557374
Cyp2c65multiple interactionsISOCYP2C9 (Homo sapiens)6480464CTDAmiodarone promotes the reaction [CYP2C9 protein results in increased metabolism of Coumarins]; Dichlorphenamide promotes the reaction [CYP2C9 protein results in increased metabolism of Coumarins]; estropipate promotes the reaction [CYP2C9 protein results in increased metabolism of Coumarins]; Niclosamide promotes the reaction [CYP2C9 protein results in increased metabolism of Coumarins]; Triiodothyronine promotes the reaction [CYP2C9 protein results in increased metabolism of Coumarins]PMID:14557374
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