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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628641
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptger4
Name: prostaglandin E receptor 4
Acc ID: CHEBI:231670
Term: Ono-AE1-329
Definition: Ono-AE1-329 is a novel agonist of the prostaglandin PGE2 receptor EP4.
Chemical ID: MESH:C461399
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptger4multiple interactionsISOPtger4 (Mus musculus)6480464CTDPTGER4 protein affects the reaction [ONO-AE1-329 inhibits the reaction [Zymosan results in increased expression of TNF mRNA]]; PTGER4 protein affects the reaction [ONO-AE1-329 inhibits the reaction [Zymosan results in increased expression of TNF protein]]; PTGER4 protein affects the reaction [ONO-AE1-329 promotes the reaction [Zymosan results in increased expression of IL10 mRNA]]; PTGER4 protein affects the reaction [ONO-AE1-329 promotes the reaction [Zymosan results in increased expression of IL10 protein]]PMID:11301049
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