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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731072
Species: Homo sapiens
RGD Object: Gene
Symbol: VEGFA
Name: vascular endothelial growth factor A
Acc ID: CHEBI:22984
Term: calcium atom
Definition: An alkaline earth metal atom that has formula Ca.
Chemical ID: MESH:D002118
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
VEGFAincreases abundanceEXP 6480464CTDVEGFA protein results in increased abundance of CalciumPMID:30524369
VEGFAmultiple interactionsEXP 6480464CTD[VEGFA protein results in increased activity of KDR protein] which results in increased abundance of Calcium; TRPC6 protein promotes the reaction [[VEGFA protein results in increased activity of KDR protein] which results in increased abundance of Calcium]; VEGFA protein promotes the reaction [[Diglycerides results in increased activity of TRPC6 protein] which results in increased abundance of Calcium]PMID:14551041
VEGFAaffects expressionISOVegfa (Rattus norvegicus)6480464CTDCalcium affects the expression of VEGFA mRNAPMID:15913539
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