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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730886
Species: Homo sapiens
RGD Object: Gene
Symbol: CREB1
Name: cAMP responsive element binding protein 1
Acc ID: CHEBI:22984
Term: calcium atom
Definition: An alkaline earth metal atom that has formula Ca.
Chemical ID: MESH:D002118
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CREB1affects expressionISOCreb1 (Rattus norvegicus)6480464CTDCalcium affects the expression of CREB1 mRNAPMID:15913539
CREB1multiple interactionsISOCreb1 (Rattus norvegicus)6480464CTD[Estradiol results in increased import of Calcium] which results in increased activity of CREB1 protein; Calcium promotes the reaction [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased phosphorylation of CREB1 protein]; Calcium promotes the reaction [Dopamine results in increased phosphorylation of CREB1 protein]PMID:14622123 PMID:15802184
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