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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62266
Species: Mus musculus
RGD Object: Gene
Symbol: Trpc3
Name: transient receptor potential cation channel, subfamily C, member 3
Acc ID: CHEBI:22984
Term: calcium atom
Definition: An alkaline earth metal atom that has formula Ca.
Chemical ID: MESH:D002118
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trpc3affects secretionEXP 6480464CTDTRPC3 protein affects the secretion of CalciumPMID:16484216
Trpc3affects transportISOTrpc3 (Rattus norvegicus)6480464CTDTRPC3 protein affects the transport of CalciumPMID:15672411
Trpc3affects transportISOTRPC3 (Homo sapiens)6480464CTDTRPC3 protein affects the transport of CalciumPMID:17351372
Trpc3increases transportISOTrpc3 (Rattus norvegicus)6480464CTDTRPC3 protein results in increased transport of CalciumPMID:18822394
Trpc3increases transportISOTRPC3 (Homo sapiens)6480464CTDTRPC3 protein results in increased transport of CalciumPMID:12700192 PMID:12736256
Trpc3multiple interactionsISOTrpc3 (Rattus norvegicus)6480464CTD1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [[Phenylephrine results in increased expression of TRPC3 protein] which results in increased transport of Calcium]; [Phenylephrine results in increased expression of TRPC3 protein] which results in increased transport of Calcium; TRPC3 protein promotes the reaction [1-oleoyl-2-acetoyl-sn-glycerol results in increased transport of Calcium]; TRPC3 protein promotes the reaction [Phenylephrine results in increased transport of Calcium]; TRPC3 protein promotes the reaction [Thapsigargin results in increased transport of Calcium]PMID:15672411 PMID:19244478
Trpc3multiple interactionsISOTRPC3 (Homo sapiens)6480464CTD1-oleoyl-2-acetylglycerol affects the reaction [TRPC3 protein affects the transport of Calcium]; 1-oleoyl-2-acetylglycerol promotes the reaction [TRPC3 protein results in increased transport of Calcium]; OXT protein promotes the reaction [TRPC3 protein results in increased transport of Calcium]; Thapsigargin promotes the reaction [TRPC3 protein results in increased transport of Calcium]PMID:12700192 PMID:17351372
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